7 research outputs found

    Technical challenges for identification in mobile environments

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    This report describes technical challenges and requirements for identification of individuals in mobile (i.e. non-stationary) environments as e.g. required by the ÂżEuropean Mobile Identification Interoperability GroupÂż (MOBIDIG). It is intended to support relevant stakeholders as law enforcement agencies or immigration offices, active in the area of identification of individuals in mobile environments. It offers some guidance for future technical work at the MOBIDIG to be respected in their work plan. Furthermore, it may be used as a first orientation for the general future work for identification in mobile environments using digital or electronically stored data. After the introduction and some background of MOBIDIG and its policy context, the document presents the intention, main objectives and some information about the scope of work of the group. The following proposals, suggestions and recommendations presented are explicitly focusing on technology. Organizational and procedural issues are out of focus of this document and need to be addressed separately in further documents.JRC.DG.G.6-Security technology assessmen

    Second ERNCIP Operators Workshop - Workshop Report

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    In order to intensify the collaboration with operators of critical infrastructure, ERNCIP has so far organised two cross-sectoral Operators’ Workshops; the first one took place in Brussels on 12-13 September, 2013 and the second one took place in Ispra on 19-20 May 2014. This document is co-written by the three moderators for the second Operators’ Workshop; Carmine Rizzo, Klaus Keus and Alois J. Sieber. The report summarises and analyses the discussions and also presents some recommendations based on the outcome..JRC.G.5-Security technology assessmen

    Pantoprazole in patients at risk for gastrointestinal bleeding in the ICU

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    BACKGROUND Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear. METHODS In this European, multicenter, parallel-group, blinded trial, we randomly assigned adults who had been admitted to the ICU for an acute condition (i.e., an unplanned admission) and who were at risk for gastrointestinal bleeding to receive 40 mg of intravenous pantoprazole (a proton-pump inhibitor) or placebo daily during the ICU stay. The primary outcome was death by 90 days after randomization. RESULTS A total of 3298 patients were enrolled; 1645 were randomly assigned to the pantoprazole group and 1653 to the placebo group. Data on the primary outcome were available for 3282 patients (99.5%). At 90 days, 510 patients (31.1%) in the pantoprazole group and 499 (30.4%) in the placebo group had died (relative risk, 1.02; 95% confidence interval [CI], 0.91 to 1.13; P=0.76). During the ICU stay, at least one clinically important event (a composite of clinically important gastrointestinal bleeding, pneumonia, Clostridium difficile infection, or myocardial ischemia) had occurred in 21.9% of patients assigned to pantoprazole and 22.6% of those assigned to placebo (relative risk, 0.96; 95% CI, 0.83 to 1.11). In the pantoprazole group, 2.5% of patients had clinically important gastrointestinal bleeding, as compared with 4.2% in the placebo group. The number of patients with infections or serious adverse reactions and the percentage of days alive without life support within 90 days were similar in the two groups. CONCLUSIONS Among adult patients in the ICU who were at risk for gastrointestinal bleeding, mortality at 90 days and the number of clinically important events were similar in those assigned to pantoprazole and those assigned to placebo. (Funded by Innovation Fund Denmark and others; SUP-ICU ClinicalTrials.gov number, NCT02467621.

    Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU

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    BACKGROUND Prophylaxis for gastrointestinal stress ulceration is frequently given to patients in the intensive care unit (ICU), but its risks and benefits are unclear. METHODS In this European, multicenter, parallel-group, blinded trial, we randomly assigned adults who had been admitted to the ICU for an acute condition (i.e., an unplanned admission) and who were at risk for gastrointestinal bleeding to receive 40 mg of intravenous pantoprazole (a proton-pump inhibitor) or placebo daily during the ICU stay. The primary outcome was death by 90 days after randomization. RESULTS A total of 3298 patients were enrolled; 1645 were randomly assigned to the pantoprazole group and 1653 to the placebo group. Data on the primary outcome were available for 3282 patients (99.5%). At 90 days, 510 patients (31.1%) in the pantoprazole group and 499 (30.4%) in the placebo group had died (relative risk, 1.02; 95% confidence interval [CI], 0.91 to 1.13; P=0.76). During the ICU stay, at least one clinically important event (a composite of clinically important gastrointestinal bleeding, pneumonia, Clostridium difficile infection, or myocardial ischemia) had occurred in 21.9% of patients assigned to pantoprazole and 22.6% of those assigned to placebo (relative risk, 0.96; 95% CI, 0.83 to 1.11). In the pantoprazole group, 2.5% of patients had clinically important gastrointestinal bleeding, as compared with 4.2% in the placebo group. The number of patients with infections or serious adverse reactions and the percentage of days alive without life support within 90 days were similar in the two groups. CONCLUSIONS Among adult patients in the ICU who were at risk for gastrointestinal bleeding, mortality at 90 days and the number of clinically important events were similar in those assigned to pantoprazole and those assigned to placebo. (Funded by Innovation Fund Denmark and others; SUP-ICU ClinicalTrials.gov number, NCT02467621 .)

    [The effect of low-dose hydrocortisone on requirement of norepinephrine and lactate clearance in patients with refractory septic shock].

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